The history of swine breeding improvement in Southeast Asia during the recent fifty years was reviewed. The progress and present breeding structure of swine breeding in Charoen Pokphand Co. LTD was discussed. Also, the swine breeding principles, genetic correlations between traits, heterosis utilization, relation between breeding and environment, promotion of market requirement, etc, were discussed. Based on the experience of fifty years work on swine production, the author gave some valuable suggestion for the swine breeding in Southeast Asia.