【Objective】 To establish a stalk flexible model of Artemisia selengensis.【Method】Based on the physical parameters of the stalk of A. selengensis, the finite element model of stalk was established by using the ANSYS software. The axial and radial mechanical properties of A. selengensis stalk at different growth positions under compression were studied. The model calculation value and experimental value were analyzed and compared.【Result】The maximum deviation of model calculation value and experimental value was 14.46%. A. selengensis stalk had anisotropic characteristics with its axial compression mechanical properties being much better compared to the radial. At three different positions, the stem breakage occurred on the edges of both ends of the loading surface under radial compression，while under axial compression, the stem breakage occurred on the loading surface, and the stress gradually receded from close to the loading area to surroundings. 【Conclusion】The mechanical properties of A. selengensis stalk can be analyzed by model simulation, and the results can provide theoretical references for reducing mechanical damage during harvesting, transportation, processing and storage of A. selengensis and for designing A. selengensis harvest machine.