遗传密码子和均一手性的起源问题
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Origin of Genetic Codon and Homochirality
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    摘要:

    针对生命起源研究领域,遗传密码及手性均一性两大难题,提出了新的思路,作者认为:原始密码子应是“3读2”三联体,由于某种氨基酸-tRNA-寡核苷酸复合体之间的聚合反应,导致原始密码子顺序同期编码二肽的同步起经的多态性则反映了进化轨迹,是原始密码子第3位碱基,分发化物结果;同时还认为,手性均一性是周转在代生命分子的独特行为,它必然同代谢系统同步起源,原始的类似糖生成途径可能起到关键性作用。

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    A new way of thinking about genetic code and homochirality, which remain the major difficulties in the field of the origin of life, is suggested. The author reasons that procodons must have been twoout-of-three triplets. They originated synchronously with the dipeptides coded thereby via polymerization of certain amino acid-tRNA-oligopeptides complexes. The polymorphism of genetic code reflecting the evolutionary track is the outcome of differentiation of the third position bases of the procodon, step by step; and that homochirality, as an unique behavior of life molecules tuming over in metabolic system,must have originated synchronously with the latter. A key role could have been played by the primitive glycogenesis-like pathway.

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肖敬平.遗传密码子和均一手性的起源问题[J].华南农业大学学报,1999,(4):120-124

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