Anaesthesic efficacy of Lumianning on the Family Felidae was observed and evaluated in Siberian tiger, Bengal tiger, jaguar, leopard, black panther and lion. Results showed that Lumianning manifested good sedative, analgesic and muscle relaxant effects and with minor side-effect.The dosages used did not differ between tigers and panthers ( P >0.05 ), but there were significant difference between those used on lions versus tigers and leopards ( P <0.01).